COMPUTER PREDICTION OF THE MEDICINAL PROPERTIES OF NEW N-ALKOXYALKYL-4-PIPERIDINEKETOXIMES

Abstract

In this article, the medicinal potential of new derivatives of N-alkoxyalkyl-4-piperidineketoximes was investigated using in silico methods. The pharmacokinetic and toxicological properties of the compounds were evaluated by computer-based ADMET profile prediction. QSAR elements were used to determine the structure–property relationship, and the potential biological activity was studied using the PASS prediction system. The results obtained showed that the structural features of the compounds under study significantly affect their pharmacokinetic properties and provide a basis for further study of these compounds in experimental research.